Isolation and Characterization of Circulating Tumor Cells in Squamous Cell Carcinoma of the Lung Using a Non-EpCAM-Based Capture Method.

The exclusion of circulating tumor cells (CTCs) that have lost epithelial antigens during the epithelial-to-mesenchymal transition (EMT) process by using Epithelial Cell Adhesion Molecule (EpCAM) based capture methods is still a matter of debate. In this study, cells obtained after depletion procedu...

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Main Authors: Cecilia Bozzetti, Federico Quaini, Anna Squadrilli, Marcello Tiseo, Caterina Frati, Costanza Lagrasta, Cinzia Azzoni, Lorena Bottarelli, Maricla Galetti, Angela Alama, Silvana Belletti, Rita Gatti, Antonio Passaro, Angela Gradilone, Andrea Cavazzoni, Roberta Alfieri, Pier Giorgio Petronini, Mara Bonelli, Angela Falco, Cecilia Carubbi, Giuseppe Pedrazzi, Rita Nizzoli, Nadia Naldi, Carmine Pinto, Andrea Ardizzoni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4646671?pdf=render