APC(CDH1) targets MgcRacGAP for destruction in the late M phase.

APC(CDH1) targets MgcRacGAP for destruction in the late M phase.

Male germ cell RacGTPase activating protein (MgcRacGAP) is an important regulator of the Rho family GTPases--RhoA, Rac1, and Cdc42--and is indispensable in cytokinesis and cell cycle progression. Inactivation of RhoA by phosphorylated MgcRacGAP is an essential step in cytokinesis. MgcRacGAP is also...

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Bibliographic Details
Main Authors: Koutarou Nishimura, Toshihiko Oki, Jiro Kitaura, Shinji Kuninaka, Hideyuki Saya, Asako Sakaue-Sawano, Atsushi Miyawaki, Toshio Kitamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3656054?pdf=render

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http://europepmc.org/articles/PMC3656054?pdf=render

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