TANC1 methylation as a novel biomarker for the diagnosis of patients with anti-tuberculosis drug-induced liver injury

Abstract We aimed to elucidate the differences in genomic methylation patterns between ADLI and non-ADLI patients to identify DNA methylation-based biomarkers. Genome-wide DNA methylation patterns were obtained using Infinium MethylationEPIC (EPIC) BeadChip array to analyze 14 peripheral blood sampl...

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Bibliographic Details
Main Authors: Dongxue Wu, Yuhong Li, Qi Ren, Shengfei Pei, Lin Wang, Luming Yang, Yingzhi Chong, Shufeng Sun, Jinqi Hao, Fumin Feng
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-96869-5