Antigenic Relatedness of Norovirus GII.4 Variants Determined by Human Challenge Sera.

The GII.4 noroviruses (NoVs) are a single genotype that is responsible for over 50% of NoV gastroenteritis epidemics worldwide. However, GII.4 NoVs have been found to undergo antigenic drifts, likely selected by host herd immunity, which raises an issue for vaccine strategies against NoVs. We previo...

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Bibliographic Details
Main Authors: Ying-Chun Dai, Xu-Fu Zhang, Ming Xia, Ming Tan, Christina Quigley, Wen Lei, Hao Fang, Weiming Zhong, Bonita Lee, Xiaoli Pang, Jun Nie, Xi Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0124945