Effects of the Total Saponins from Rosa laevigata Michx Fruit against Acetaminophen-Induced Liver Damage in Mice via Induction of Autophagy and Suppression of Inflammation and Apoptosis

Effects of the Total Saponins from Rosa laevigata Michx Fruit against Acetaminophen-Induced Liver Damage in Mice via Induction of Autophagy and Suppression of Inflammation and Apoptosis

The effect of the total saponins from Rosa laevigata Michx fruit (RLTS) against acetaminophen (APAP)-induced liver damage in mice was evaluated in the present paper. The results showed that RLTS markedly improved the levels of liver SOD, CAT, GSH, GSH-Px, MDA, NO and iNOS, and the activities of seru...

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Bibliographic Details
Main Authors: Deshi Dong, Lina Xu, Xu Han, Yan Qi, Youwei Xu, Lianhong Yin, Kexin Liu, Jinyong Peng
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Molecules
Subjects:
acetaminophen
hepatoprotective effect
liver injury
Rosa laevigata Michx
total saponins
Online Access:http://www.mdpi.com/1420-3049/19/6/7189

Internet

http://www.mdpi.com/1420-3049/19/6/7189

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