Vagus Nerve Stimulation Promotes Epithelial Proliferation and Controls Colon Monocyte Infiltration During DSS-Induced Colitis

Vagus Nerve Stimulation Promotes Epithelial Proliferation and Controls Colon Monocyte Infiltration During DSS-Induced Colitis

Background: We previously showed increased susceptibility to dextran sulfate sodium (DSS)-induced colitis in vagotomized mice. Here, we evaluated whether vagus nerve stimulation (VNS) is able to reduce the severity of DSS colitis and aimed to unravel the mechanism involved.Methods: Colitis was induc...

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Bibliographic Details
Main Authors: Elisa Meroni, Nathalie Stakenborg, Pedro J. Gomez-Pinilla, Michelle Stakenborg, Javier Aguilera-Lizarraga, Morgane Florens, Marcello Delfini, Veronica de Simone, Gert De Hertogh, Gera Goverse, Gianluca Matteoli, Guy E. Boeckxstaens
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Medicine
Subjects:
vagus nerve stimulation
dextran sodium sulfate
inflammatory bowel diseases
macrophage - cell
epithelial barrier
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.694268/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.694268/full

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