Protective effects of coumestrol on lipopolysaccharide-induced acute lung injury via the inhibition of proinflammatory mediators and NF-κB activation

Protective effects of coumestrol on lipopolysaccharide-induced acute lung injury via the inhibition of proinflammatory mediators and NF-κB activation

Few studies have reported on the antioxidant and anti-inflammatory properties of coumestrol (CM). In this study, CM not only significantly attenuated inflammation in acute lung injury (ALI) mice but also reduced the production of nitric oxide (NO), tumour necrosis factor-α (TNF-α) and interleukin-6...

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Bibliographic Details
Main Authors: Heung Joo Yuk, Jae Won Lee, Hyun Ah Park, Ok-Kyoung Kwon, Kyeong-Hwa Seo, Kyung-Seop Ahn, Sei-Ryang Oh, Hyung Won Ryu
Format: Article
Language:English
Published: Elsevier 2017-07-01
Series:Journal of Functional Foods
Subjects:
ALI
LPS
Coumestrol
TNF-α
IL-6
NF-κB
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617302165

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http://www.sciencedirect.com/science/article/pii/S1756464617302165

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