Decreased RXRα is associated with increased β-catenin/TCF4 in 56-Fe-induced intestinal tumors

Decreased RXRα is associated with increased β-catenin/TCF4 in 56-Fe-induced intestinal tumors

Although it is known that accumulation of oncogenic β-catenin is critical for intestinal tumorigenesis, the underlying mechanisms have not yet been fully explored. Post-translational β-catenin level is regulated via the adenomatous polyposis coli (APC)-dependent as well as the APC-independent ubiqui...

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Bibliographic Details
Main Authors: Shubhankar eSuman, Santosh eKumar, Albert J. Fornace, Kamal eDatta
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Oncology
Subjects:
Heavy Ions
Radiation
Proteasome
beta-Catenin
space radiation
Intestinal tumor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00218/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00218/full

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