Natural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways.

Complex traits, including common disease-related traits, are affected by many different genes that function in multiple pathways and networks. The apoptosis, MAPK, Notch, and Wnt signalling pathways play important roles in development and disease progression. At the moment we have a poor understandi...

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Main Authors: Kapil Dev Singh, Bernd Roschitzki, L Basten Snoek, Jonas Grossmann, Xue Zheng, Mark Elvin, Polina Kamkina, Sabine P Schrimpf, Gino B Poulin, Jan E Kammenga, Michael O Hengartner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4795773?pdf=render