The c.*52 <i>A/G</i> and c.*773 <i>A/G</i> Genetic Variants in the UTR′3 of the <i>LDLR</i> Gene Are Associated with the Risk of Acute Coronary Syndrome and Lower Plasma HDL-Cholesterol Concentration

The c.*52 <i>A/G</i> and c.*773 <i>A/G</i> Genetic Variants in the UTR′3 of the <i>LDLR</i> Gene Are Associated with the Risk of Acute Coronary Syndrome and Lower Plasma HDL-Cholesterol Concentration

Dyslipidemia has a substantial role in the development of acute coronary syndrome (ACS). Low-density lipoprotein receptor (LDLR) plays a critical role in plasma lipoprotein hemostasis, which is involved in the formation of atherosclerotic plaque. This study aimed to evaluate whether <i>LDLR<...

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Bibliographic Details
Main Authors: Gilberto Vargas-Alarcon, Oscar Perez-Mendez, Julian Ramirez-Bello, Rosalinda Posadas-Sanchez, Hector Gonzalez-Pacheco, Galileo Escobedo, Betzabe Nieto-Lima, Elizabeth Carreon-Torres, Jose Manuel Fragoso
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomolecules
Subjects:
genetics
single nucleotide polymorphism
acute coronary syndrome
Online Access:https://www.mdpi.com/2218-273X/10/10/1381

Internet

https://www.mdpi.com/2218-273X/10/10/1381

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