Claudin-1 Expression Is Elevated in Colorectal Cancer Precursor Lesions Harboring the BRAF V600E Mutation

BACKGROUND: Sessile serrated adenomas/polyps (SSA/P) are now recognised precursors of colorectal cancer (CRC) including cancers harbouring somatic BRAF (V600E) mutations. While the morphological diagnostic criteria of SSA/P have been established, distinguishing between small/early SSA/P and microves...

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Bibliographic Details
Main Authors: Maria Caruso, Kim Y.C. Fung, James Moore, Gemma V. Brierley, Leah J. Cosgrove, Michelle Thomas, Glenice Cheetham, Emma Brook, Louise M. Fraser, Teresa Tin, Ha Tran, Andrew Ruszkiewicz
Format: Article
Language:English
Published: Elsevier 2014-08-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523314000643