Why do eukaryotic proteins contain more intrinsically disordered regions?

Intrinsic disorder is more abundant in eukaryotic than prokaryotic proteins. Methods predicting intrinsic disorder are based on the amino acid sequence of a protein. Therefore, there must exist an underlying difference in the sequences between eukaryotic and prokaryotic proteins causing the (predict...

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Bibliographic Details
Main Authors: Walter Basile, Marco Salvatore, Claudio Bassot, Arne Elofsson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007186