Maternal Dexamethasone Exposure Alters Synaptic Inputs to Gonadotropin-Releasing Hormone Neurons in the Early Postnatal Rat

Maternal Dexamethasone Exposure Alters Synaptic Inputs to Gonadotropin-Releasing Hormone Neurons in the Early Postnatal Rat

Maternal dexamethasone (DEX; a glucocorticoid receptor agonist) exposure delays pubertal onset and alters reproductive behaviour in the adult offspring. However, little is known whether maternal DEX exposure affects the offspring’s reproductive function by disrupting the gonadotropin-releasing hormo...

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Bibliographic Details
Main Authors: Wei Ling Lim, Marshita Mohd Idris, Felix Suresh Kevin, Tomoko Soga, Ishwar Parhar
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Endocrinology
Subjects:
Preoptic Area
Reproduction
glucocorticoid
GnRH neuron
Synapsin-I
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00117/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00117/full

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