Pterostilbene Attenuates Fructose-Induced Myocardial Fibrosis by Inhibiting ROS-Driven Pitx2c/miR-15b Pathway

Excessive fructose consumption induces oxidative stress and myocardial fibrosis. Antioxidant compound pterostilbene has cardioprotective effect in experimental animals. This study is aimed at investigating how fructose drove fibrotic responses via oxidative stress in cardiomyocytes and explored the...

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Bibliographic Details
Main Authors: Lin-Lin Kang, Dong-Mei Zhang, Rui-Qing Jiao, Shu-Man Pan, Xiao-Juan Zhao, Yan-Jing Zheng, Tian-Yu Chen, Ling-Dong Kong
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2019/1243215