Exercise-Mediated Lowering of Glutamine Availability Suppresses Tumor Growth and Attenuates Muscle Wasting

Summary: Glutamine is a central nutrient for many cancers, contributing to the generation of building blocks and energy-promoting signaling necessary for neoplastic proliferation. In this study, we hypothesized that lowering systemic glutamine levels by exercise may starve tumors, thereby contributi...

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Bibliographic Details
Main Authors: Katrine S. Pedersen, Francesco Gatto, Bo Zerahn, Jens Nielsen, Bente K. Pedersen, Pernille Hojman, Julie Gehl
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220301620