EFNB2 facilitates cell proliferation, migration, and invasion in pancreatic ductal adenocarcinoma via the p53/p21 pathway and EMT

EFNB2 facilitates cell proliferation, migration, and invasion in pancreatic ductal adenocarcinoma via the p53/p21 pathway and EMT

Ephrin-2 (EFNB2) is expressed at abnormally high levels in some neoplasms, such as squamous cell carcinoma of the head and neck and colorectal cancer. Its overexpression is associated with the malignant progression of tumors. However, the expression of EFNB2 in pancreatic ductal adenocarcinoma (PDAC...

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Bibliographic Details
Main Authors: Feng Zhu, Shang-Nan Dai, Da-Lai Xu, Chao-Qun Hou, Tong-Tai Liu, Qiu-Yang Chen, Jun-Li Wu, Yi Miao
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Pancreatic ductal adenocarcinoma
Ephrin 2
Receptor tyrosine kinase
Tumor progression
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220301621

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http://www.sciencedirect.com/science/article/pii/S0753332220301621

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