Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract

Background: Zoonotically transmitted coronaviruses are responsible for three disease outbreaks since 2002, including the current COVID-19 pandemic, caused by SARS-CoV-2. Its efficient transmission and range of disease severity raise questions regarding the contributions of virus-receptor interaction...

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Bibliographic Details
Main Authors: Miguel E. Ortiz, Andrew Thurman, Alejandro A. Pezzulo, Mariah R. Leidinger, Julia A. Klesney-Tait, Philip H. Karp, Ping Tan, Christine Wohlford-Lenane, Paul B. McCray, Jr., David K. Meyerholz
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:EBioMedicine
Subjects:
Lung
Expression
Alveolar type II cells
Ciliated cells
Immunohistochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420303522

Internet

http://www.sciencedirect.com/science/article/pii/S2352396420303522

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