Emerging Technologies and Generic Assays for the Detection of Anti-Drug Antibodies

Anti-drug antibodies induced by biologic therapeutics often impact drug pharmacokinetics, pharmacodynamics response, clinical efficacy, and patient safety. It is critical to assess the immunogenicity risk of potential biotherapeutics in producing neutralizing and nonneutralizing anti-drug antibodies...

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Bibliographic Details
Main Authors: Michael A. Partridge, Shobha Purushothama, Chinnasamy Elango, Yanmei Lu
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2016/6262383