Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas

Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas

Abstract Background The receptor tyrosine kinases (RTKs) play critical roles in the development of cancers. Clear cell renal cell carcinoma (ccRCC) accounts for 75% of the RCC. The previous studies on the RTKs in ccRCCs mainly focused on their gene expressions. The activation and function of the RTK...

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Bibliographic Details
Main Authors: Qing Zhang, Jian-He Liu, Jing-Li Liu, Chun-Ting Qi, Lei Yan, Yu Chen, Qiang Yu
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Cancer
Subjects:
Receptor tyrosine kinases (RTKs)
Activation and function
Clear cell renal cell carcinomas (ccRCCs)
Targeted therapy
PDGFRβ
Stroma cells
Online Access:http://link.springer.com/article/10.1186/s12885-019-6159-2

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http://link.springer.com/article/10.1186/s12885-019-6159-2

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