Diurnal Variation in Systemic Acute Inflammation and Clinical Outcomes Following Severe Blunt Trauma

Diurnal Variation in Systemic Acute Inflammation and Clinical Outcomes Following Severe Blunt Trauma

Animal studies suggest that the time of day is a determinant of the immunological response to both injury and infection. We hypothesized that due to this diurnal variation, time of injury could affect the systemic inflammatory response and outcomes post-trauma and tested this hypothesis by examining...

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Bibliographic Details
Main Authors: Akram M. Zaaqoq, Rami A. Namas, Othman Abdul-Malak, Khalid Almahmoud, Derek Barclay, Jinling Yin, Ruben Zamora, Matthew R. Rosengart, Timothy R. Billiar, Yoram Vodovotz
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
circadian rhythm
blunt trauma
chemokines
nervous system
acute inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02699/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02699/full

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