The consequences of multiple simultaneous C-type lectin-ligand interactions: DCIR alters the endo-lysosomal routing of DC-SIGN

The consequences of multiple simultaneous C-type lectin-ligand interactions: DCIR alters the endo-lysosomal routing of DC-SIGN

Antigen-presenting cells are equipped with multiple receptors to allow proper pathogen recognition and capture. C-type lectin receptors (CLRs) recognize glycan structures on pathogens and endogenous glycoproteins for internalization and antigen processing and presentation. Often, the glycan specific...

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Bibliographic Details
Main Authors: Juan J. eGarcia-Vallejo, Karien eBloem, Leon eKnippels, Johan eGarssen, Sandra evan Vliet, Yvette eVan Kooyk
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Immunology
Subjects:
Dendritic Cells (DC)
Antigen uptake
Mannose receptor (MR)
dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN)
dendritic cell immunoreceptor (DCIR)
macrophage galactose-type lectin (MGL)
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00087/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00087/full

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