Monocarboxylate transporter 8 modulates the viability and invasive capacity of human placental cells and fetoplacental growth in mice.

Monocarboxylate transporter 8 (MCT8) is a well-established thyroid hormone (TH) transporter. In humans, MCT8 mutations result in changes in circulating TH concentrations and X-linked severe global neurodevelopmental delay. MCT8 is expressed in the human placenta throughout gestation, with increased...

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Main Authors: Elisavet Vasilopoulou, Laurence S Loubière, Heike Heuer, Marija Trajkovic-Arsic, Veerle M Darras, Theo J Visser, Gendie E Lash, Guy S Whitley, Christopher J McCabe, Jayne A Franklyn, Mark D Kilby, Shiao Y Chan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3680392?pdf=render