Cell Behaviors during Closure of the Choroid Fissure in the Developing Eye

Coloboma is a defect in the morphogenesis of the eye that is a consequence of failure of choroid fissure fusion. It is among the most common congenital defects in humans and can significantly impact vision. However, very little is known about the cellular mechanisms that regulate choroid fissure clo...

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Bibliographic Details
Main Authors: Gaia Gestri, Naiara Bazin-Lopez, Clarissa Scholes, Stephen W. Wilson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
eye
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2018.00042/full