Activation of brain metabolism and fos during limbic seizures: The role of Locus Coeruleus

Activation of brain metabolism and fos during limbic seizures: The role of Locus Coeruleus

The noradrenergic nucleus Locus Coeruleus (LC) densely innervates limbic structures. In rats, the damage to LC by the neurotoxin DSP-4, converts episodic limbic seizures induced by bicuculline infusion in the anterior piriform cortex (APC) into self-sustaining status epilepticus (SE). SE induced by...

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Bibliographic Details
Main Authors: Filippo S. Giorgi, Fabio Blandini, Emanuela Cantafora, Francesca Biagioni, Marie-Therese Armentero, Livia Pasquali, Francesco Orzi, Luigi Murri, Antonio Paparelli, Francesco Fornai
Format: Article
Language:English
Published: Elsevier 2008-06-01
Series:Neurobiology of Disease
Subjects:
Locus Coeruleus
Norepinephrine
Status epilepticus
[14C]2-Deoxyglucose
Fos
Piriform cortex
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108000417

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http://www.sciencedirect.com/science/article/pii/S0969996108000417

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