MicroRNA-34a promotes the senescence and apoptosis of human lens epithelial cells by up-regulating Cdc42 and Rac1

AIM: To observe the effect and mechanism of MicroRNA-34a on senescence and apoptosis of human lens epithelial cell line SRA01/04.<p>METHODS: MicroRNA-34a expression levels in ARC lens and transparent lens epithelial cells were detected by qRT-PCR. MicroRNA-34a mimics, MicroRNA-34a inhibitors a...

Full description

Bibliographic Details
Main Authors: Wen Lan, Zhi-Jun Chen, Lu Zhou
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2020-05-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2020/5/202005005.pdf