A Polyvinylpyrrolidone-Based Supersaturable Self-Emulsifying Drug Delivery System for Enhanced Dissolution of Cyclosporine A

A Polyvinylpyrrolidone-Based Supersaturable Self-Emulsifying Drug Delivery System for Enhanced Dissolution of Cyclosporine A

A novel supersaturable self-emulsifying drug delivery system (S-SEDDS) of cyclosporine A (CyA)—a poorly water-soluble immunosuppressant—was constructed in order to attain an apparent concentration–time profile comparable to that of conventional SEDDS with reduced use of oil, surfactant, and cosolven...

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Bibliographic Details
Main Authors: Dae Ro Lee, Myoung Jin Ho, Young Wook Choi, Myung Joo Kang
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Polymers
Subjects:
cyclosporine A
self-emulsifying drug delivery system (SEDDS)
supersaturation
apparent concentration
precipitation inhibitor
polyvinylpyrrolidone
Online Access:http://www.mdpi.com/2073-4360/9/4/124

Internet

http://www.mdpi.com/2073-4360/9/4/124

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