Cancer immunotherapies targeting the PD-1 signaling pathway

Cancer immunotherapies targeting the PD-1 signaling pathway

Abstract Immunotherapy has recently emerged as the fourth pillar of cancer treatment, joining surgery, radiation, and chemotherapy. While early immunotherapies focused on accelerating T-cell activity, current immune-checkpoint inhibitors take the brakes off the anti-tumor immune responses. Successfu...

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Bibliographic Details
Main Authors: Yoshiko Iwai, Junzo Hamanishi, Kenji Chamoto, Tasuku Honjo
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Biomedical Science
Subjects:
PD-1
PD-L1
Cancer immunotherapy
Immune checkpoint
Online Access:http://link.springer.com/article/10.1186/s12929-017-0329-9

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http://link.springer.com/article/10.1186/s12929-017-0329-9

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