Surface NKG2C Identifies Differentiated αβT-Cell Clones Expanded in Peripheral Blood

Surface NKG2C Identifies Differentiated αβT-Cell Clones Expanded in Peripheral Blood

T cells that express CD56 in peripheral blood of healthy humans represent a heterogeneous and poorly studied subset. In this work, we analyzed this subset for NKG2C expression. In both CD56+ and CD56− subsets most of the NKG2C+ T cells had a phenotype of highly differentiated CD8+ TEMRA cells. The C...

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Bibliographic Details
Main Authors: Elena I. Kovalenko, Ivan V. Zvyagin, Maria A. Streltsova, Artem I. Mikelov, Sofya A. Erokhina, William G. Telford, Alexander M. Sapozhnikov, Yury B. Lebedev
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
TCR repertoire
NKT-like cells
NKG2C
T cell differentiation
cytomegalovirus infection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.613882/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.613882/full

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