Association of antibody responses to the conserved Plasmodium falciparum merozoite surface protein 5 with protection against clinical malaria.

BACKGROUND: Plasmodium falciparum merozoite surface protein 5 (PfMSP5) is an attractive blood stage vaccine candidate because it is both exposed to the immune system and well conserved. To evaluate its interest, we investigated the association of anti-PfMSP5 IgG levels, in the context of responses t...

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Bibliographic Details
Main Authors: Ronald Perraut, Charlotte Joos, Cheikh Sokhna, Hannah E J Polson, Jean-François Trape, Adama Tall, Laurence Marrama, Odile Mercereau-Puijalon, Vincent Richard, Shirley Longacre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4105459?pdf=render