Genomic Mapping of Splicing-Related Genes Identify Amplifications in <i>LSM1</i>, <i>CLNS1A,</i> and <i>ILF2</i> in Luminal Breast Cancer

Genomic Mapping of Splicing-Related Genes Identify Amplifications in <i>LSM1</i>, <i>CLNS1A,</i> and <i>ILF2</i> in Luminal Breast Cancer

Alternative splicing is an essential biological process, which increases the diversity and complexity of the human transcriptome. In our study, 304 splicing pathway-related genes were evaluated in tumors from breast cancer patients (TCGA dataset). A high number of alterations were detected, includin...

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Bibliographic Details
Main Authors: María del Mar Noblejas-López, Igor López-Cade, Jesús Fuentes-Antrás, Gonzalo Fernández-Hinojal, Ada Esteban-Sánchez, Aránzazu Manzano, José Ángel García-Sáenz, Pedro Pérez-Segura, Miguel De La Hoya, Atanasio Pandiella, Balázs Győrffy, Vanesa García-Barberán, Alberto Ocaña
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
splicing pathway
luminal breast cancer
BET inhibitors
Online Access:https://www.mdpi.com/2072-6694/13/16/4118

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https://www.mdpi.com/2072-6694/13/16/4118

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