Protein kinase A and C regulate leak potassium currents in freshly isolated vascular myocytes from the aorta.

We tested the hypothesis that protein kinase A (PKA) inhibits K2P currents activated by protein kinase C (PKC) in freshly isolated aortic myocytes. PDBu, the PKC agonist, applied extracellularly, increased the amplitude of the K2P currents in the presence of the "cocktail" of K(+) channel...

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Bibliographic Details
Main Authors: Sébastien Hayoz, Luis Cubano, Hector Maldonado, Rostislav Bychkov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3781042?pdf=render