Poly(I:C) promotes TNFα/TNFR1-dependent oligodendrocyte death in mixed glial cultures

Poly(I:C) promotes TNFα/TNFR1-dependent oligodendrocyte death in mixed glial cultures

<p>Abstract</p> <p>Background</p> <p>Activation of glial cells via toll-like receptors (TLRs) and other intracellular pathogen recognition receptors promotes the release of potentially toxic acute phase reactants such as TNFα and nitric oxide into the extracellular spac...

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Bibliographic Details
Main Authors: Li Jianrong, Steelman Andrew J
Format: Article
Language:English
Published: BMC 2011-08-01
Series:Journal of Neuroinflammation
Subjects:
poly(I:C)
oligodendrocyte death
TLR
TNFα
microglia activation
astrocytes
Online Access:http://www.jneuroinflammation.com/content/8/1/89

Internet

http://www.jneuroinflammation.com/content/8/1/89

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