The Roles of Epithelial-to-Mesenchymal Transition (EMT) and Mesenchymal-to-Epithelial Transition (MET) in Breast Cancer Bone Metastasis: Potential Targets for Prevention and Treatment

The Roles of Epithelial-to-Mesenchymal Transition (EMT) and Mesenchymal-to-Epithelial Transition (MET) in Breast Cancer Bone Metastasis: Potential Targets for Prevention and Treatment

Many studies have revealed molecular connections between breast and bone. Genes, important in the control of bone remodeling, such as receptor activator of nuclear kappa (RANK), receptor activator of nuclear kappa ligand (RANKL), vitamin D, bone sialoprotein (BSP), osteopontin (OPN), and calcitonin,...

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Bibliographic Details
Main Author: Binnaz Demirkan
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Journal of Clinical Medicine
Subjects:
breast cancer bone metastasis
epithelial-to-mesenchymal transition (EMT)
mesenchymal-to-epithelial transition (MET)
prevention
treatment
Online Access:http://www.mdpi.com/2077-0383/2/4/264

Internet

http://www.mdpi.com/2077-0383/2/4/264

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