SP1-induced long non-coding RNA SNHG6 facilitates the carcinogenesis of chondrosarcoma through inhibiting KLF6 by recruiting EZH2

Abstract Small nucleolar RNA host gene 6 (SNHG6) is a newly discovered long non-coding RNA (lncRNA), while the regulatory mechanism of SNHG6 in chondrosarcoma is largely unknown. Here we found that SNHG6 expression was upregulated and showed positive correlation with the progression of chondrosarcom...

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Main Authors: Fei-Fei Pu, De-Yao Shi, Ting Chen, Yu-Xuan Liu, Bin-Long Zhong, Zhi-Cai Zhang, Wei-Jian Liu, Qiang Wu, Bai-Chuan Wang, Zeng-Wu Shao, Tong-Chuan He, Jian-Xiang Liu
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-03352-6