The Colayer Method as an Efficient Way to Genetically Modify Mesencephalic Progenitor Cells Transplanted into 6-OHDA Rat Model of Parkinson's Disease

Exogenous cell replacement represents a potent treatment option for Parkinson's disease. However, the low survival rate of transplanted dopaminergic neurons (DA) calls for methodological improvements. Here we evaluated a method to combine transient genetic modification of neuronal progenitor ce...

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Bibliographic Details
Main Authors: Andreas Ratzka, Ieva Kalve, Meltem Özer, André Nobre, Maike Wesemann, Julia Jungnickel, Christiane Köster-Patzlaff, Olga Baron, Claudia Grothe
Format: Article
Language:English
Published: SAGE Publishing 2012-04-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X586774