Neutrophil extracellular traps are downregulated by glucocorticosteroids in lungs in an equine model of asthma

Neutrophil extracellular traps are downregulated by glucocorticosteroids in lungs in an equine model of asthma

Abstract Background Severe neutrophilic asthma is poorly responsive to glucocorticosteroids (GC). Neutrophil extracellular traps (NETs) within the lungs have been associated with the severity of airway obstruction and inflammation in asthma, and were found to be unaffected by GC in vitro. As IL-17 i...

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Bibliographic Details
Main Authors: Amandine Vargas, Roxane Boivin, Patricia Cano, Yoana Murcia, Isabelle Bazin, Jean-Pierre Lavoie
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Respiratory Research
Subjects:
Neutrophil activation
Neutrophil extracellular traps and glucocorticosteroids
Online Access:http://link.springer.com/article/10.1186/s12931-017-0689-4

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http://link.springer.com/article/10.1186/s12931-017-0689-4

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