Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases

As an adaptive response to the overloading with misfolded proteins in the endoplasmic reticulum (ER), ER stress plays critical roles in maintaining protein homeostasis in the secretory pathway to avoid damage to the host. Such a conserved mechanism is accomplished through three well-orchestrated pat...

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Bibliographic Details
Main Authors: Beichu eGuo, Zihai eLi
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00242/full