Incorporation of genetic model parameters for cost-effective designs of genetic association studies using DNA pooling

<p>Abstract</p> <p>Background</p> <p>Studies of association methods using DNA pooling of single nucleotide polymorphisms (SNPs) have focused primarily on the effects of "machine-error", number of replicates, and the size of the pool. We use the non-centrality...

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Bibliographic Details
Main Authors: Mendell Nancy R, Haynes Chad, Finch Stephen J, Ji Fei, Gordon Derek
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/8/238