Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection.

Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection.

Studying SIV infection of natural host monkey species, such as sooty mangabeys, has provided insights into the immune changes associated with these nonprogressive infections. Mangabeys maintain immune health despite high viremia or the dramatic CD4 T cell depletion that can occur following multitrop...

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Bibliographic Details
Main Authors: Vasudha Sundaravaradan, Ramsey Saleem, Luca Micci, Melanie A Gasper, Alexandra M Ortiz, James Else, Guido Silvestri, Mirko Paiardini, John D Aitchison, Donald L Sodora
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3694849?pdf=render

Internet

http://europepmc.org/articles/PMC3694849?pdf=render

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