Treatment With Tafamidis Slows Disease Progression in Early-Stage Transthyretin Cardiomyopathy

Background: Transthyretin cardiomyopathy (TTR-CM) is a progressive, fatal disease caused by the accumulation of misfolded transthyretin (TTR) amyloid fibrils in the heart. Tafamidis is a kinetic stabilizer of TTR that inhibits misfolding and amyloid formation. Methods: In this post hoc analysis, dat...

Full description

Bibliographic Details
Main Authors: Marla B Sultan, Balarama Gundapaneni, Jennifer Schumacher, Jeffrey H Schwartz
Format: Article
Language:English
Published: SAGE Publishing 2017-09-01
Series:Clinical Medicine Insights: Cardiology
Online Access:https://doi.org/10.1177/1179546817730322