Polyunsaturated fatty acid production by Yarrowia lipolytica employing designed myxobacterial PUFA synthases

Sustainable sources are needed to meet the demand for long-chain polyunsaturated fatty acids. Here the authors construct an artificial biosynthetic gene cluster in Y. lipolytica capable of producing a high concentration of PUFAs.

Bibliographic Details
Main Authors: Katja Gemperlein, Demian Dietrich, Michael Kohlstedt, Gregor Zipf, Hubert S. Bernauer, Christoph Wittmann, Silke C. Wenzel, Rolf Müller
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-12025-8