Methotrexate-Induced Accumulation of Fluorescent Annexin V in Collagen-Induced Arthritis

We examined the accumulation of Cy5.5-labeled annexin V in the paws of mice with and without collagen-induced arthritis, with and without methotrexate (MTX) treatment, by near-infrared fluorescence imaging. Fluorescence reflectance imaging (FRI) of paws was performed 48 hr after MTX injection and at...

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Bibliographic Details
Main Authors: Andreas Wunder, Eyk Schellenberger, Umar Mahmood, Alexei Bogdanov, Ulf Müller-Ladner, Ralph Weissleder, Lee Josephson
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2005-01-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1162/15353500200504142