Association between Regimen Composition and Treatment Response in Patients with Multidrug-Resistant Tuberculosis: A Prospective Cohort Study.

<h4>Background</h4>For treating multidrug-resistant tuberculosis (MDR TB), the World Health Organization (WHO) recommends a regimen of at least four second-line drugs that are likely to be effective as well as pyrazinamide. WHO guidelines indicate only marginal benefit for regimens based...

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Main Authors: Courtney M Yuen, Ekaterina V Kurbatova, Thelma Tupasi, Janice Campos Caoili, Martie Van Der Walt, Charlotte Kvasnovsky, Martin Yagui, Jaime Bayona, Carmen Contreras, Vaira Leimane, Julia Ershova, Laura E Via, HeeJin Kim, Somsak Akksilp, Boris Y Kazennyy, Grigory V Volchenkov, Ruwen Jou, Kai Kliiman, Olga V Demikhova, Irina A Vasilyeva, Tracy Dalton, J Peter Cegielski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-12-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1001932