Electrophysiological characteristics of a SCN5A voltage sensors mutation R1629Q associated with Brugada syndrome.

Electrophysiological characteristics of a SCN5A voltage sensors mutation R1629Q associated with Brugada syndrome.

Brugada syndrome (BrS) is an inherited arrhythmogenic syndrome leading to sudden cardiac death, partially associated with autosomal dominant mutations in SCN5A, which encodes the cardiac sodium channel alpha-subunit (Nav1.5). To date some SCN5A mutations related with BrS have been identified in volt...

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Bibliographic Details
Main Authors: Zhipeng Zeng, Jieqiong Zhou, Yuxi Hou, Xiaojing Liang, Ziguan Zhang, Xuejing Xu, Qiang Xie, Weihua Li, Zhengrong Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3805610?pdf=render

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http://europepmc.org/articles/PMC3805610?pdf=render

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