Peptide: MHC-based DNA vaccination strategy to activate natural killer cells by targeting killer cell immunoglobulin-like receptors

Background Natural killer (NK) cells are increasingly being recognized as agents for cancer immunotherapy. The killer cell immunoglobulin-like receptors (KIRs) are expressed by NK cells and are immunogenetic determinants of the outcome of cancer. In particular, KIR2DS2 is associated with protective...

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Bibliographic Details
Main Authors: Aymen Al-Shamkhani, Marta E Polak, Pauline Rettman, Matthew D Blunt, Rebecca J Fulton, Andres F Vallejo, Leidy Y Bastidas-Legarda, Laura España-Serrano, Christelle Retiere, Salim I Khakoo
Format: Article
Language:English
Published: BMJ Publishing Group 2021-05-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/9/5/e001912.full