Tumor-Associated Macrophages Induce Endocrine Therapy Resistance in ER+ Breast Cancer Cells

Tumor-Associated Macrophages Induce Endocrine Therapy Resistance in ER+ Breast Cancer Cells

Antiestrogenic adjuvant treatments are first-line therapies in patients with breast cancer positive for estrogen receptor (ER+). Improvement of their treatment strategies is needed because most patients eventually acquire endocrine resistance and many others are initially refractory to anti-estrogen...

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Bibliographic Details
Main Authors: Andrés M. Castellaro, María C. Rodriguez-Baili, Cecilia E. Di Tada, Germán A. Gil
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cancers
Subjects:
macrophages
tumor microenvironment
breast cancer
estrogen receptor
tamoxifen
endocrine resistance
TNF-α
IL-6
NF-κB
Online Access:https://www.mdpi.com/2072-6694/11/2/189

Internet

https://www.mdpi.com/2072-6694/11/2/189

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