Characterization of an intratracheal aerosol challenge model of Brucella melitensis in guinea pigs.

B. melitensis is considered the most virulent of the Brucella species, and a need exists for an improved laboratory animal model of infection that mimics natural transmission and disease. Guinea pigs are highly susceptible to infection with Brucella spp. and develop a disease syndrome that mimics na...

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Bibliographic Details
Main Authors: Martha E Hensel, Daniel G Garcia-Gonzalez, Sankar P Chaki, James Samuel, Angela M Arenas-Gamboa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212457