Doxorubicin Is Key for the Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Combination in Differentiated H9c2 Cells

Currently, a common therapeutic approach in cancer treatment encompasses a drug combination to attain an overall better efficacy. Unfortunately, it leads to a higher incidence of severe side effects, namely cardiotoxicity. This work aimed to assess the cytotoxicity of doxorubicin (DOX, also known as...

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Bibliographic Details
Main Authors: Maria Pereira-Oliveira, Ana Reis-Mendes, Félix Carvalho, Fernando Remião, Maria de Lourdes Bastos, Vera Marisa Costa
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Biomolecules
Subjects:
FAC
Online Access:http://www.mdpi.com/2218-273X/9/1/21