Low miR-214-5p Expression Correlates With Aggressive Subtypes of Pediatric ALCL With Non-Common Histology

Low miR-214-5p Expression Correlates With Aggressive Subtypes of Pediatric ALCL With Non-Common Histology

The unsatisfactory cure rate of relapsing ALK-positive Anaplastic Large-Cell Lymphoma (ALCL) of childhood calls for the identification of new prognostic markers. Here, the small RNA landscape of pediatric ALK-positive ALCL was defined by RNA sequencing. Overall, 121 miRNAs were significantly dysregu...

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Bibliographic Details
Main Authors: Piero Di Battista, Federica Lovisa, Enrico Gaffo, Ilaria Gallingani, Carlotta C. Damanti, Anna Garbin, Lavinia Ferrone, Elisa Carraro, Marta Pillon, Luca Lo Nigro, Rossella Mura, Marco Pizzi, Vincenza Guzzardo, Angelo Paolo Dei Tos, Alessandra Biffi, Stefania Bortoluzzi, Lara Mussolin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
ALCL
childhood
miRNA
prognosis
biomarker
RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.663221/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.663221/full

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