Islet autoimmunity identifies a unique pattern of impaired pancreatic beta-cell function, markedly reduced pancreatic beta cell mass and insulin resistance in clinically diagnosed type 2 diabetes.

Islet autoimmunity identifies a unique pattern of impaired pancreatic beta-cell function, markedly reduced pancreatic beta cell mass and insulin resistance in clinically diagnosed type 2 diabetes.

There is a paucity of literature describing metabolic and histological data in adult-onset autoimmune diabetes. This subgroup of diabetes mellitus affects at least 5% of clinically diagnosed type 2 diabetic patients (T2DM) and it is termed Latent Autoimmune Diabetes in Adults (LADA). We evaluated in...

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Main Authors: Angela Subauste, Roberto Gianani, Annette M Chang, Cynthia Plunkett, Susan L Pietropaolo, Ying-Jian Zhang, Emma Barinas-Mitchell, Lewis H Kuller, Andrzej Galecki, Jeffrey B Halter, Massimo Pietropaolo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4165581?pdf=render

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http://europepmc.org/articles/PMC4165581?pdf=render

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